A fluorescent-labeled microcystin-LR terbium cryptate
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چکیده
منابع مشابه
Matrix Effects on the Microcystin-LR Fluorescent Immunoassay Based on Optical Biosensor
Matrix effects on the microcystin-LR fluorescent immunoassay based on the evanescent wave all-fiber immunosensor (EWAI) and their elimination methods were studied. The results indicated that PBS and humic acid did not affect the monitoring of samples under the investigated conditions. When the pH was less than 6 or higher than 8, the fluorescence signals detected by immunosensor systems were ob...
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Background: Previous studies have been reported on the toxicity of Microcystin-LR, which is produced by cyanobacterial growth in fish, such as Heteropneustes fossilis (H. fossilis). However, no studies have been conducted on the effects of Microcystin-LR on the prolactin cells of H. fossilis. Methods: H. fossilis fish were intraperitoneally injected with Microcystin-LR (2.5μg/25g) and sacrif...
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Proteasome degrades proteins in eukaryotic cells. As such, the proteasome is crucial in cell cycle and function. This study proved that microcystin-LR (MC-LR), which is a toxic by-product of algal bloom, can target cellular proteasome and selectively inhibit proteasome trypsin-like (TL) activity. MC-LR at 1 nM can inhibit up to 54% of the purified 20S proteasome TL activity and 43% of the prote...
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Cyanobacteria, such as the toxin producer Microcystis aeruginosa, are predicted to be favored by global warming both directly, through elevated water temperatures, and indirectly, through factors such as prolonged stratification of waterbodies. M. aeruginosa is able to produce the hepatotoxin microcystin, which causes great concern in freshwater management worldwide. However, little is known ab...
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ژورنال
عنوان ژورنال: Journal of the Brazilian Chemical Society
سال: 2006
ISSN: 0103-5053
DOI: 10.1590/s0103-50532006000200005